A 34-year-old San Francisco woman accused of fatally beating her boyfriend Sunday inside their South of Market residence pleaded not guilty to murder today in San Francisco Superior Court.

Police said Kira Roueche called 911 from an apartment at the Henry Hotel at 106 Sixth St., where the couple had been living, at about 8 p.m. Sunday to report that 42-year-old Cameron Miller was unconscious. Paramedics arrived and pronounced him dead.

Homicide inspectors interviewed Roueche and arrested her early the next morning.

Prosecutors allege Roueche used a vodka bottle and a clock to beat Miller until he died.

Roueche wept as she entered the courtroom this morning. She pleaded not guilty to one count of murder with a use-of-a-deadly-weapon allegation and two counts of assault with a deadly weapon resulting in great bodily injury.

Roueche was ordered held on $1 million bail and is due back in court Dec. 1 for a date-setting hearing.

Her attorney, Kleigh Hathaway, said after the hearing that she couldn’t comment on the specifics of the case, as she had just started to review police reports.

“I’m very confident that she’s going to be exonerated,” Hathaway said.

District attorney’s office spokesman Brian Buckelew said Miller had an acute pre-existing medical condition at the time of his death.

The medical examiner has yet to rule on an exact cause of Miller’s death, but Buckelew said his condition “appears to have left him especially vulnerable.”

Roueche has a prior conviction from 2006 for drug possession, according to the district attorney’s Office.

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